PIK3C2A and breast cancer: To better understand the molecular mechanism by which PI3KC2α overexpression promotes metastasis, human breast cancer cell lines expressing low levels of PI3KC2α, like MCF7 and MDA‐MB‐468, were engineered with a PiggyBac (PB) transposomal vector to produce a stable overexpression of PI3KC2α (Figure S1m, Supporting Information).