SFTPB and newborn respiratory distress syndrome: Pathogenic variants in genes that encode key components of pulmonary surfactant include surfactant protein B (SP-B, SFTPB gene), surfactant protein C (SP-C, SFTPC gene), and the ATP-binding cassette transporter A3 (ABCA3, ABCA3 gene) and are leading inherited causes of neonatal respiratory distress syndrome (RDS) and childhood interstitial lung disease (chILD) (Garmany et al., 2008).