When male and female patients with T2DM were given resveratrol (1 g/day, oral capsule) in conjunction with their current medication (oral hypoglycemic agent and/or insulin) for 45 days, FBG, HbA1c, fasting serum insulin, and insulin resistance were all significantly reduced compared to the placebo group [170]. The gene discussed is INS; the disease is type 2 diabetes mellitus.