The KEGG pathway was mainly enriched in 61 signaling pathways, such as endocrine resistance (hsa01522), AGE-RAGE in diabetic complications (hsa04933), estrogen signaling pathway (hsa04915), fluid shear stress and atherosclerosis (hsa05418), Hepatitis B (hsa05161), IL-17 (hsa04657), serotonergic synapse (hsa04726), relaxin signaling pathway (hsa04926), human immunodeficiency virus 1 infection (hsa05170), and microRNAs (miRNAs) in cancer (hsa05206). The gene discussed is RENBP; the disease is cancer.