Further, a total of five KEGG pathways, namely, hsa04978: mineral absorption; hsa04550: signaling pathways regulating pluripotency of stem cells; hsa04261: adrenergic signaling in cardiomyocytes; hsa04360: axon guidance; and hsa05205: proteoglycans in cancer, enriched nine downstream DEmRNAs, in which we noticed that ATP2B4 activated both in KEGG pathways, hsa04978: mineral absorption and hsa04261: adrenergic signaling in cardiomyocytes. Here, ATP2B4 is linked to cancer.