TMC5 and cancer: We further evaluated the expression of TMC5 in different pathological stages in human cancers and uncovered a statistically significant correlation between the TMC5 level and cancer stages in BRCA, CESC, ESCA, KICH, LIHC, LUSC, OV, and PAAD, Especially, in LIHC, LUSC, and PAAD, the TMC5 level was positively correlated with cancer stages (Figure 1D).