TMC7 and hepatocellular carcinoma: In the meantime, TMC7 was identified as a potential prognostic biomarker for pancreatic cancer (Cheng et al., 2019); the same association was discovered between TMC8 and hepatocellular carcinoma (HCC) (Lu et al., 2017), TMC4, and breast cancer (Aushev et al., 2019), TMC3 and colorectal cancer (CRC) (Zhou et al., 2020), TMC8 and head and neck squamous cancer (Lin et al., 2021).