For cancers including BLCA (p < 0.001), BRCA (p < 0.001), HNSC (p < 0.001), KIRC (p < 0.001), KIRP (p < 0.05), LUAD (p < 0.001), LUSC (p < 0.001), PAAD (p < 0.001), PRAD (p < 0.001), and UCEC (p < 0.001), TMC5 was significantly differentially methylated between tumor and normal tissues (Figure 6A). This evidence concerns the gene TMC5 and cancer.