In a high-quality meta-analysis (26), plasma and urine NGAL (AUC: 0.71; 95% CI, 0.64–0.77 and AUC:0.72; 95% CI, 0.66–0.79, respectively), plasma and urine plasma cystatin C (AUC: 0.69; 95% CI, 0.63–0.74 and AUC: 0.63; 95% CI, 0.37–0.89, respectively), urine KIM-1 (AUC: 0.72; 95% CI, 0.59–0.84), and urine L-FABP (AUC: 0.72; 95% CI, 0.60–0.85) showed moderate diagnostic value for CSA-AKI. The gene discussed is CST3; the disease is acute kidney injury.