Some BFSSs addressed in this review (G-NASH, ClinLipMet, and enhanced liver fibrosis test) measure components that are not readily available, seldom ordered, or expensive, such as the PNPLA3 genotype, CK-18 M30 fragments, Golgi protein 73, or the tissue inhibitor of metalloproteinase 1. This evidence concerns the gene PNPLA3 and metabolic dysfunction-associated steatohepatitis.