Supplementary Table 1 demonstrates the unadjusted and adjusted OR and p-value of the SNPs at the ABO locus. As blood type frequencies vary across the ancestry groups, the confounding effect of ancestry was evaluated by adjusting for ethnicity. The first ten eigenvectors were used in subsequent analyses for adjustment to population stratification. Following these adjustments, eight SNPs were identified on the ABO gene locus that was associated with COVID-19 severity, all located in the 3'-UTR region (Table 3). The gene discussed is ABO; the disease is COVID-19.