The different coronaviruses that participate in human infections have different receptors, so HCoV-229E uses CD13 as receptor (80), HCoV-OC43 and HKU1 use Sialic Acid receptors (81, 82), and NL63, SARS-CoV, and SARS-CoV-2 use ACE2 as their receptor (Figure 2). Here, ACE2 is linked to infection.