Increasing evidence has revealed that the expression level of LINC00346 is significantly upregulated in schizophrenia (Ghafouri-Fard et al., 2021), nasopharyngeal carcinoma (Cui et al., 2020), lung cancer (Wang et al., 2017), hepatocellular carcinoma (HCC) (Jin et al., 2020; Yin et al., 2020; Zhang and Chen, 2020), glioma (Yang C. et al., 2020; Chen X. et al., 2020), colorectal cancer (CRC) (Tong et al., 2020), cutaneous squamous cell carcinoma (Piipponen et al., 2020), breast cancer (Li et al., 2020d), gastric cancer, and pancreatic cancer (Table 1). This evidence concerns the gene PRECSIT and hepatocellular carcinoma.