After literature mining in PubMed literature retrieval system, we found that some of these 23 genes have been confirmed to be related to breast cancer, including 12 genes, ADH1A, ADH1C, AKR1C4, ALDH3A1, CYP1A2, CYP2B6, CYP2C18, CYP2C19, CYP3A4, CYP3A7, GSTA1, RXRG. This evidence concerns the gene ADH1A and breast cancer.