Both the scotopic and photopic Kcnj13 cKO Cre+ ERG a- and b-waves are extinguished, consistent with the loss of the entire photoreceptor layer shown in Figures 4F,G, 5B,C, as well as the retinitis pigmentosa phenotype seen in humans with loss of function KCNJ13 mutations, or in some cases highly attenuated, consistent with the patchy degeneration seen in a relatively small group or mice (Supplementary Figure S1). Here, KCNJ13 is linked to retinitis pigmentosa.