To examine whether the presence of HDAC6 inclusions in c9FTD/ALS might be due to an interaction between HDAC6 and DPR proteins, HEK293T cells expressing Myc-tagged HDAC6 were co-transfected with green fluorescent protein (GFP) or GFP-tagged DPR repeat constructs, including GFP-(GA)50, GFP-(GP)47, and GFP-(GR)50. Here, MYC is linked to amyotrophic lateral sclerosis.