HAX1 and Decreased total neutrophil count: In a recent study comparing two subjects with bi-allelic mutations in CLPB and three subjects with mono-allelic mutations, different patterns of oligomeric CLPB and HAX1, whose genetics variants have been associated to neutropenia, were interpreted as a retention of HAX1 in inefficient CLPB oligomers in the patients (Wortmann et al., 2021).