IL10 and atherosclerosis: For example, MSCs mediate cardiomyocytes immune responses through STAT3 to improve cardiac function, regulate c-Fos protein by secreting exosomes and enhance Tregs polarization to improve cardiac function in ischemia-reperfusion injured mice, reduce inflammatory response in the MI area by increasing IL-10 levels, and treat atherosclerosis by regulating the phenotypic transition between macrophage inflammation and phenotype.