DVL1 and Umbilical hernia: Vertebral segmentation defects and ribs fusion occur in the recessive form linked to ROR2 mutations (MIM# 268310) (127) whereas umbilical hernia and supernumerary teeth are more common in the autosomal dominant forms due to WNT5A (MIM# 180700), DVL1 (MIM# 616331), DVL3 (MIM# 616894) mutations (128).