NFKB1 and infection: Many signaling pathways have been reported to be involved in the regulation of KSHV de novo infection, such as MAPK, NF-κB, antiviral and inflammation signaling pathways (Lee et al., 2016; Uppal et al., 2018; Wei and Lan, 2018; Zhao et al., 2018; Golas et al., 2020).