Besides, KEGG pathway analysis showed that the enriched pathways of up-regulated lncRNAs were related to immunity, cell adhesion molecules, JAK-STAT, Toll-like receptor and PI3K-Akt signaling while the enriched pathways of down-regulated lncRNAs were associated with Hippo signaling, pluripotency of stem cells, lysine degradation and propanoate metabolism in cancer (Figure 1D). This evidence concerns the gene AKT1 and cancer.