Thirteen and fourteen factors including “do not resuscitate (DNR)” status, age, weight loss >10%, dyspnea, functional dependence, ascites, chronic steroid use, active sepsis, serum creatinine level, serum albumin level, serum white blood cell (WBC), serum hematocrit and acuity of surgical procedure, and procedure type were found to be independently associated with postoperative complications and death, respectively. The gene discussed is ALB; the disease is Sepsis.