WASHC2C and hepatocellular carcinoma: In this study, we found that FAM21C was highly expressed in HCC tissues by bioinformatics analysis, and its high expression predicted a poor prognosis for HCC patients; Meanwhile, we further verified that FAM21C was highly expressed in HCC tissues using TMAs, and its high expression could promote malignant progression of HCC, and this result was also confirmed in vitro and in vivo.