In the old lung cancer group, there were genes significantly concurrent with actionable driver genes (CDKN2A, NF1): FAT1, LRP1B, ARID2 with CDKN2A; EPHB1 with NF1, and genes significantly exclusive with actionable driver genes (EGFR, KRAS): MLL2, STK11, KRAS with EGFR (Figure 3C). Here, LRP1B is linked to lung cancer.