Corollary to our finding, it was recently reported that increased expression of Mediator subunit MED1 induces upregulation of the miR-191/425 cluster (namely, miR-100-5p, miR-191-5p, miR-193b-3p, miR-205-5p, miR-326, miR-422a and miR-425-5p), in breast cancer, and that this promotes cell proliferation and migration (35). Here, MED1 is linked to breast carcinoma.