Due to the small number of normal samples in TCGA, we integrated normal tissue data from the GTEx database with TCGA tumor tissue data to analyze the expression differences of RPP25 in 33 types of tumors (Sample size of each type of cancer were displayed in the x-coordinate of Figure 2B), and from the results (Figure 2B) we found that RPP25 expression was upregulated in the vast majority of tumor tissues compared to normal tissues, except for GBM, LGG, OV, and PRAD. This evidence concerns the gene RPP25 and cancer.