Collectively, ROS accumulation following oxidative stress induces the production of chemokines, thus promoting the infiltration of T cells trafficking into vitiligo lesions, providing insight into the importance of the CXCL9/CXCL10-CXCR3 axis that orchestrates the migration of immune cells involved in the progression and maintenance of vitiligo, indicating potential targets for treating vitiligo. This evidence concerns the gene CXCR3 and vitiligo.