Analysis of gene expression profiling revealed the elevations of IFN-γ and IFN-γ-induced genes in the serum and lesional skin from patients with vitiligo and mouse models of vitiligo, and researchers found that the IFN-γ levels were correlated with the progression and maintenance of vitiligo, indicating that IFN-γ could serve as a reliable risk factor in vitiligo patients [37–42]. Here, IFNG is linked to vitiligo.