Specifically, ACACA, FBP1, BAP1, FH, HIF1A, KRAS, MTOR, VHL, PBRM1, PRKAA1, and SETD2 were downregulated, while ACLY, AKT1, MYC, G6PD, HIF2A, SLC2A1, and TP53 were upregulated in ccRCC tissues compared with normal tissue (Figure 2(a)). Here, ACLY is linked to nonpapillary renal cell carcinoma.