Specifically, ACACA, FBP1, BAP1, FH, HIF1A, KRAS, MTOR, VHL, PBRM1, PRKAA1, and SETD2 were downregulated, while ACLY, AKT1, MYC, G6PD, HIF2A, SLC2A1, and TP53 were upregulated in ccRCC tissues compared with normal tissue (Figure 2(a)). This evidence concerns the gene PRKAA1 and nonpapillary renal cell carcinoma.