Finally, progesterone stimulates the production of proinflammatory cells and upregulates the expression of cytokines and proteins such as IL10, IL-1β, IL-5, IL-6, IL-22, IL-4, IL-17A, TNFα, and GATA 3 through the regulation of receptors in asthma [12, 107, 118, 119]. The gene discussed is IL1B; the disease is asthma.