In glioma stem cells, it has been confirmed that BRD4 could enhance the activity of the Wnt/β-catenin pathway via promoting the expression of miR-142-5p, and BRD4 has also been identified as a suppressor of P53 to promote the progression of acute myeloid leukemia [28, 29]. The gene discussed is TP53; the disease is acute myeloid leukemia.