However, compared with the T2DM group, the weight of rats in the DAPA group was notably higher (P < 0.05), the ratios of HW/BW and LVW/BW were obviously lower (P < 0.05), and the mRNA expression levels of ANP and BNP in rat myocardial tissue were markedly lower (Figures 1(e)–1(g)). This evidence concerns the gene NPPB and type 2 diabetes mellitus.