TNF and rheumatoid arthritis: Conversely, the serum levels of TNF-α, TNF-γ, IL-1, IL-5, IL-6, IL-13, IL-17, and IL-1β in JWJGF, prednisone, and GTW groups were all decreased to a different extent compared with the control group, and the expression level of Jin-Wu-Jian-Gu decoction in high-dose group was substantially lower than RA group (P < 0.01).