BECN1 and neoplasm: And also in the form of moderately and strongly positive Beclin1 and LC3B expression and high Gleason score (score 9) and high Gleason group (group 5) and these results were in accordance with other studies that explained that as there is a “dual-faced” role of autophagy either tumor suppressor or tumor promotor according to the stage of the malignancy (24, 28).