Of the 60 cases of CRC included in this study, 17 patients (28.33%) had negative STC2 staining (7 no staining and 10 weak staining, and both were considered negative according to our scoring system), 32 patients (53.33%) showed mild positive staining, and 11 patients (18.33%) demonstrated intense positive staining (Figure 1). Here, STC2 is linked to colorectal carcinoma.