CD40LG and AL amyloidosis: Out of the variety of AL amyloidosis, immunoglobulin M (IgM) related AL represents around only 6–10% of affected patients, and 54% of these cases are related to underlying non-Hodgkin's lymphoma including Waldenström's macroglobulinemia, and the remaining cases are related to pure clonal plasma cell neoplasm [5–7].