PDCD1 and non-small cell lung carcinoma: Currently, the marketed PD-1 inhibitors including nivolumab, pembrolizumab, and tislelizumab are mainly used for the treatment of melanoma and non-small-cell lung cancer, and their efficacy against renal cell carcinoma, bladder cancer, and Hodgkin's lymphoma is still under large-scale clinical trials [10, 11].