Duan et al. (2020) disclosed that miR-654-3p hinders cell proliferation, invasion, and sphere formation in breast cancer. Xiong and others manifested that miR-654-3p constrains cell viability and hastens cell apoptosis via targeting RASAL2 in non–small cell lung cancer (Xiong et al., 2021). Here, RASAL2 is linked to breast cancer.