One study has demonstrated that inhibition of MEG3 after stroke attenuates hypoxia-induced apoptosis by decreasing its combination with miR-181b and consequently reducing the expression of 12/15-LOX expression (Liu et al., 2016); another study verifies that knockdown of TUG1 promotes cell survival after oxygen-glucose deprivation insults by serving as an miR-9 sponge (Chen et al., 2017). Here, MEG3 is linked to stroke disorder.