Abundant type vicollagen in lung tissue α5 (COL6A5), rs13062453, rs1497305, and rs77123808 of COL6A5 polymorphism are associated with lung cancer risk in Chinese Han population, and the overall survival rate of patients with low expression of the COL6A5 gene is poor (Duan et al., 2020). This evidence concerns the gene COL6A5 and lung cancer.