HMOX1 and neoplasm: Proteins related to cell proliferation, growth, and apoptosis like BCL-X, HIF-1α, HNF-3β, and HO-1/HMOX1 were also downregulated, that is, related to tumor progression, whereas upregulation of E-cadherin (CDH1) was observed after chrysin treatment (Figure 3B, Figure 3C and Table 2).