It induces cell cycle arrest, inhibits cell adhesion and tumor cell–induced angiogenesis, and induces apoptosis in various types of cancer, and also downregulates pathways including AKT (Khoo et al., 2010; Kasala et al., 2015; Ryu et al., 2017; Lim et al., 2018). The gene discussed is AKT1; the disease is neoplasm.