We found that in the CIP group, there was a significant increase in the expression level of CD79B and RALGPS2 (P < 0.05; Figure 5A), while the expression of marker-IL32 in CIP CD4+Tregs was lower than that in the Control group (P < 0.05; Figure 5A). Here, CD4 is linked to hereditary sensory and autonomic neuropathy.