Indeed, our study demonstrates the following: (i) Although HC and LABC patients did not differ in their UTR haplotypes’ frequencies, the UTR-4 haplotype was associated with unfavorable disease status regarding tumor size and the presence of DTC, whereas UTR-7 or UTR-3 were related to low tumor sizes, absence of DTC, and high soluble HLA-G levels, respectively. Here, HLA-G is linked to neoplasm.