Moreover, Yan and co-workers found that miR-512-5p was poorly expressed in GBM tissues and cells, and exosomes derived from miR-512-5p-transfected BMSCs were internalized by U87 cells, thus interfering with GBM cell proliferation and inducing cell cycle arrest through negatively regulating Jagged 1 (JAG1) (138). The gene discussed is JAG1; the disease is glioblastoma.