BTG3 and systemic lupus erythematosus: According to the 2019 European League Against Rheumatism/American College of Rheumatology, the classification criteria for SLE had a sensitivity of 96.1% and a specificity of 93.4% using positive ANA as an entry criteria, weighted criteria in 7 clinical areas (neuropsychiatric, hematologic, constitutional, mucocutaneous, serosal, musculoskeletal and renal), 3 immunologic domains (antiphospholipid antibodies, low complements, anti-Sm, and anti-dsDNA as SLE-specific antibodies), and a classification threshold score of ≥10 (out of a theoretical maximum of 51) (6).