WT and Adrb2-/- Sham animals had significantly lower synovitis scores at the 4 week (WT p=0.003; Adrb2-/- p<0.001), 8 week (WT p<0001; Adrb2-/- p<0.001) and 12 week (WT p<0001; Adrb2-/- p<0.001) time points compared to the respective DMM animals (Figure 1B). Here, ADRB2 is linked to synovitis.