IFNG and infection: Moreover, STAT1 signaling, which is an important regulator of IFN-γ signaling, was significantly blocked (p < 0.01) by C. parvum in the mice of the Inf.Unt group at day 5 and 15 post-infection compared with the NC, Inf.Par, Inf.Chit, and Uni.Chit groups (Figures 3A, C).