Consistent with previous findings, BDL mice developed overt liver injury and cholestasis as reflected by significant increases in serum bilirubin and ALT levels vs sham control mice (ALT: sham 12.1 ± 2.2 U/L vs BDL 754.0 ± 77.8 U/L; p<0.02; total bilirubin: sham 9.2 ± 8.2 μmol/L vs BDL 262.0 ± 29.6 μmol/L; p<0.05; n=4-6 mice/group). This evidence concerns the gene GPT and cholestasis.