CCL2 and Multiple Organ Failure: This abnormal elevation of inflammatory cytokines, such as interleukin (IL)-1, IL-6, IL-10, interferon γ (IFN-γ), monocyte chemotactic protein-1 (MCP-1), and granulocyte-macrophage colony-stimulating factor, can interact with the complement and coagulation systems, leading to acute respiratory distress syndrome, disseminated intravascular coagulation, and even multiple organ failure (9).