TOP2A and cancer: This result is consistent with the previous research on other cancer biomarkers: CCNB2 (30), UBE2C (31), BUB1B (32–34), TPX2 (35), CCNA2 (36), CCNB1 (37, 38), MELK (35, 39), TOP2A (40–42), PBK, and KIF11.