The analysis of samples from the cBioPortal database demonstrated that the change rates of mRNA levels were 0.2% for SKA1, 0.9% for SKA2, and 1.1% for SKA3 for LGG; 0.1% for SKA1, 0.3% for SKA2, and 0.9% for SKA3 for GBM, with increased expression for SKA3, correlated with gene amplification in a subset of the LGG and GBM tumor samples (Supplementary Figure 2). The gene discussed is SKA3; the disease is glioblastoma.