CCL5 and eosinophilic esophagitis: They present receptors for eotaxin-1, -2, -3, RANTES, MIP-1α, MCP-2, -3, -4, and lipid mediators like Platelet Activating Factor (PAF), Leukotriene B4 (LTB4) and C4 (LTC4) (Shukla et al., 2015) and, upon activation, release cationic granule proteins, reactive oxygen species, lipid mediators, enzymes, growth factors and cytokines, largely responsible for the esophageal modifications seen in EoE.