IL-13 is overexpressed in the esophageal mucosa of EoE patients (Blanchard et al., 2010), induces a gene transcript profile similar to the EoE-specific esophageal transcriptome (Kc et al., 2015), and has effects on eosinophil recruitment, esophageal barrier function, and tissue remodeling (Blanchard et al., 2007; Brightling et al., 2010; Zuo et al., 2010; Sherrill et al., 2014a). The gene discussed is IL13; the disease is eosinophilic esophagitis.