Some clinical parameters (heart rate at the admission (Lourenço et al., 2016), blood pressure, renal failure (Hummel et al., 2015) or protein biomarkers [NT-proBNP (Fonarow et al., 2007), ST2 (Shah and Januzzi, 2010), galectin-3 (Lainscak et al., 2010)] or other scores were used to this end. This evidence concerns the gene NPPB and kidney failure.