The study suggests that the chemopreventive effect displayed by quercetin in the DMBA-induced carcinogenesis model could be on account of suppression of NF-κB pathway by quercetin, followed by the modulation in the expression of NF-κB target genes Bax and Bcl-2, which led to apoptosis and tumor regression. The gene discussed is NFKB1; the disease is neoplasm.